FUNDED PROJECTS:
HEART DISEASE

All funded projects

cartell MaratóIn the 2014 Marató, which dealt with heart disease, 121 projects were presented and these were assessed by 59 scientists specialising in these diseases, according to their quality, methodology and relevance This assessment was managed by the Agency for Health Quality and Assessment of Catalonia, of the Catalan Ministry of Health.
In accordance with the proposal of the scientific Advisory Committee of the Fundació La Marató de 3Cat, the Board agreed to distribute € 10,306,474 to the following 43 research projects of excellence:

Perioperative myocardial ischaemia: application of troponin monitoring, financial analysis and further knowledge in physiopathology

  • Dr. Pablo Alonso Coello
    Institut de Recerca Hospital de la Santa Creu i Sant Pau
Fund: 199.003,60 €

iPS-derived cardiomyocytes for cardiac damage and regeneration

  • Dr. Antoni Bayés Genís
    Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
  • Dra. Mercè Martí Gaudes
    Centre Medicina Regenerativa de Barcelona
Fund: 298.468,75 €

Calibration and discrimination of the SCORE (Systematic Coronary Risk Evaluation) model for low-risk countries, as well as the new risk equation of the US American College of Cardiology-American Heart Association

  • Dr. Carlos Brotons Cuixart
    EAP Sardenya
Fund: 115.375,00 €

Genetic and molecular bases of right-ventricle arrhythmogenic myocardiopathy: transfer to clinical practice

  • Dr. Ramon Brugada Terradellas
    Centre de Genètica Cardiovascular - Institut d'Investigació Biomèdica de Girona
Fund: 199.375,00 €

Early detection and prevention of sudden neonatal death using electrocardiogram and genetic study of massive ultrasequencing

  • Dr. Òscar Campuzano Larrea
    Centre de Genètica Cardiovascular - Institut d'Investigació Biomèdica de Girona
Fund: 187.937,50 €

Mechanisms for formation of intracoronary thrombus during acute myocardial infarction with ST elevation in diabetic and non-diabetic patients: a comprehensive approach to the morphology of the culpable lesion

  • Dr. Àngel Ramon Cequier Fillat
    Hospital Universitari de Bellvitge
  • Dra. Sílvia Barceló Batllori
    Institut d'Investigació Biomèdica de Bellvitge
Fund: 298.016,10 €

Dilatation of the ascendant aorta and coronary aneurisms in patients with systemic vasculitis (giant cell arteritis and Kawasaki disease). Role of the HIF pathway in vascular remodelling/inflammation

  • Dra. M. Cinta Cid Xutglà
    Institut d'Investigació Biomèdica August Pi i Sunyer
  • Dra. Sílvia Martín Puig
    Centro Nacional de Investigaciones Cardiovasculares Carlos III - Madrid
Fund: 300.000,00 €

Creation of a new impedance-mapping system for ablation of ventricular arrhythmias in humans: transactional development

  • Dr. Juan M. Cinca Cuscullola
    Institut de Recerca Hospital de la Santa Creu i Sant Pau
  • Dr. Xavier Rosell Ferrer
    Escola Tècnica Superior d'Enginyeria Industrial - Universitat Politècnica de Catalunya
Fund: 299.625,00 €

Genomic diagnosis of coronary disease

  • Dr. Josep Comín Colet
    Institut d'Investigació Biomèdica de Bellvitge
  • Dr. Roderic Guigó
    Centre de Regulació Genòmica
Fund: 297.858,66 €

Pulmonary ultrasound in situ in the diagnosis of heart failure: diagnostic accuracy and correlation with emerging cardiac biomarkers

  • Dra. Maria del Mar Domingo Teixidor
    Institut d'Investigació Hospital Universitari Germans Trias i Pujol
Fund: 199.081,25 €

Developments and application of models of atrial myocytes to investigate mechanisms that confer on patients a high risk of atrial fibrillation

  • Dr. Blas Echebarria Domínguez
    Escola Politècnica Superior d'Edificació de Barcelona - Universitat Politècnica de Catalunya
Fund: 112.000,00 €

New predictors of coronary cardiopathy: circulating endothelial microparticles, functionality of the HDL particles and composition in fatty acids of the cellular membranes

  • Dr. Ramon Estruch Riba
    Institut d'Investigació Biomèdica August Pi i Sunyer
  • Dra. Montserrat Fitó Colomer
    Institut Hospital Mar d'Investigacions Mèdiques
  • Dr. Jordi Salas Salvadó
    Institut d'Investigació Sanitària Pere Virgili - Reus
Fund: 397.157,23 €

Aneurisms of the ascendant aorta: bimolecular and biomechanical factors

  • Dr. Arturo Evangelista Masip
    Institut de Recerca Hospital Universitari Vall d'Hebron
  • Juan Miguel Redondo Moya
    Centro Nacional de Investigaciones Cardiovasculares Carlos III - Madrid
  • Dr. Per Eriksson
    Karolinska Institutet Stockholm
Fund: 400.000,00 €

Safety, effectiveness and cost-effectiveness in medium and long term of antithrombotic therapy in patients with acute myocardial infarction with ST elevation in clinical practice

  • Dr. Ignacio Ferreira-Gonzalez
    Institut de Recerca Hospital Universitari Vall d'Hebron
Fund: 160.000,00 €

Association between iron levels and coronary disease, diabetes and metabolic syndrome: a population-based cohort study

  • Dra. Gemma Flores Mateo
    Institut d'Investigació en Atenció Primària Jordi Gol - Reus
Fund: 42.931,25 €

Combination of an adipose pedicle with myocardial matrices enriched with multifunctional extracellular vehicles by cardiac tissue engineering: preclinical and clinical studies

  • Dra. Carolina Gálvez Montón
    Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
Fund: 197.218,75 €

Adrenergic ?3 agonist treatment in secondary chronic pulmonary hypertension in heart failure: phase 2 randomised placebo-controlled clinical trial

  • Dra. Ana García Álvarez
    Hospital Clínic i Provincial de Barcelona
  • Dr. Valentí Fuster Carulla
    Centro Nacional de Investigaciones Cardiovasculares Carlos III - Madrid
  • Dra. Eulàlia Roig Minguell
    Institut de Recerca Hospital de la Santa Creu i Sant Pau
Fund: 399.750,00 €

Comparison of vasomotor function and coronary flow of patients treated with metallic versus absorbable stents at one year postimplantation

  • Dr. Josep Gómez Lara
    Institut d'Investigació Biomèdica Hospital Universitari de Bellvitge
Fund: 199.936,06 €

Micro-RNA as a new marker of cardiovascular fibrosis and echocardiographic progression in patients with degenerative aortic stenosis

  • Dra. Begoña Benito Villabriga
    Hospital Mar d'Investigacions Mèdiques
Fund: 135.556,25 €

The adenosine receptors as a new target for treatment of atrial fibrillation: biomarkers, stratification of the cardiovascular risk and therapy

  • Dr. Leif Hove Madsen
    CSIC-Institut d'Investigacions Biomèdiques de Barcelona
  • Dr. Francisco Ciruela Alférez
    Institut d'Investigació Biomèdica de Bellvitge
Fund: 299.322,78 €

Diagnostic, prognostic and therapeutic value of the LRP1 receptor in cardiovascular disease

  • Dra. Concepción Vicenta Llorente Cortés
    CSIC-Institut d'Investigacions Biomèdiques de Barcelona
Fund: 199.511,25 €

Study and manipulation of the embryonic programme of the epicardium, a new focus for heart repair

  • Dra. Ofèlia Maria Martínez Estrada
    Facultat de Biologia - Universitat de Barcelona
Fund: 199.998,75 €

Immunorregulating molecules and miARN as therapeutic targets in coronary disease and acute coronary syndrome

  • Dr. José Martínez González
    CSIC-Institut d'Investigacions Biomèdiques de Barcelona
  • Dr. Francisco Sánchez Madrid
    Hospital Universitario de la Princesa - Madrid
Fund: 300.000,00 €

Preventing premature coronary disease in Catalonia by increasing the diagnosis of familial hypercholesterolaemia

  • Dr. Lluís Masana Marín
    Institut d'Investigació Sanitària Pere Virgili Reus - Reus
  • Dr. Francisco Blanco Vaca
    Institut de Recerca Hospital de la Santa Creu i Sant Pau
Fund: 291.835,00 €

Emergency room identification of patients with low-risk acute heart failure and development of a scale to identify them and improve the evolution of those who are discharged from ER

  • Dr. Òscar Miró Andreu
    Institut d'Investigació Biomèdica August Pi i Sunyer
Fund: 66.500,00 €

Clinical and experimental study of the relationship between CMI and vancomycin in methicillin-sensitive Staphylococcus aureus (MSSA) and the prognosis of left infectious endocarditis by MSSA

  • Dr. Josep Maria Miró Meda
    Institut d'Investigació Biomèdica August Pi i Sunyer
Fund: 199.876,25 €

Non-invasive characterisation of the tissues of the left atrium to guide the ablation of the atrial fibrillation and to predict the results of the procedure, as well as the progression of the disease

  • Dr. Lluís Mont Girbau
    Institut d'Investigació Biomèdica August Pi i Sunyer
  • Dra. Marta de Antonio Ferrer
    Institut d'Investigació Hospital Universitari Germans Trias i Pujol
Fund: 296.902,50 €

Research in atrial fibrillation in Catalonia (AFRICAT)

  • Dr. Joan Montaner Villalonga
    Institut de Recerca Hospital Universitari Vall d'Hebron
  • Dr. Ángel Alonso Pedrote Martínez
    Hospitales Universitarios Virgen del Rocío - Sevilla
  • Dr. Josep Lluís Clua Espuny
    CAP El Temple - Institut Català de la Salut - Tortosa
Fund: 400.000,00 €

Effects of therapy with intravenous ferric carboxymaltose in comparison with oral iron therapy in patients with heart failure with preserved ejection fraction and iron deficit. PREFER

  • Dr. José Luis Morales Rull
    Hospital Universitari Arnau de Vilanova - Lleida
Fund: 28.725,00 €

Role of resident macrophages and fibroblasts in myocardial remodelling and tissue regeneration after myocardial infarction: contribution of the GAS6-TAM system

  • Dr. José Tomás Ortiz Pérez
    Institut d'Investigació Biomèdica August Pi i Sunyer
  • Dr. Pablo García de Frutos
    Institut Investigacions Biomèdiques de Barcelona
  • Dr. Andrés Hidalgo Alonso
    Centro Nacional de Investigaciones Cardiovasculares Carlos III - Madrid
Fund: 397.611,25 €

Early diagnosis of renal insufficiency during acute heart failure (EDRIAHF)

  • Dra. Teresa Padró Capmany
    Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Fund: 194.625,00 €

An approach from systems biology to the study of congenital cardiac malformations: identification of genetic, epigenetic and environmental factors in human and mouse cardiac tissue

  • Dr. Luis A. Pérez Jurado
    Universitat Pompeu Fabra
  • Dr. Alexander Damian Heine Suñer
    Hospital Universitari Son Espases - Palma
Fund: 299.135,00 €

Role of the new cardiomyosins FGF21 and Metrnl in cardiac damage caused by alcoholism and arterial hypertension

  • Dra. Anna Planavila Porta
    Facultat de Biologia - Universitat de Barcelona
  • Dr. Joaquim Fernández Solà
    Institut d'Investigació Biomèdica August Pi i Sunyer
Fund: 298.963,75 €

Investigation of genetic and mechanistic interactors in familial cardiomyopathy through advanced disease modelling

  • Dr. Ángel Raya Chamorro
    Centre Medicina Regenerativa de Barcelona
  • Dr. José Luis de la Pompa Mínguez
    Centro Nacional de Investigaciones Cardiovasculares Carlos III - Madrid
  • Dr. Juan Ramón Gimeno Blanes
    Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca - Múrcia
Fund: 399.875,00 €

Detection of structural alterations in coronary stents by means of non-invasive technology based on microwave radiation

  • Dr. Oriol Rodríguez Leor
    Institut d'Investigació Hospital Universitari Germans Trias i Pujol
  • Dr. Javier Tejada Palacios
    Facultat de Física - Universitat de Barcelona
Fund: 299.858,75 €

Role of connexin 43 in post myocardial infarction cicatrisation, in adverse remodelling of the left ventricle, and in heart failure

  • Dr. Antonio Rodríguez Sinovas
    Institut de Recerca Hospital Universitari Vall d'Hebron
Fund: 196.573,75 €

Role of advanced glycation end products (AGE) in damage by ischaemia-reperfusion of the old diabetic heart: from rat to human

  • Dr. Marisol Ruiz Meana
    Institut de Recerca Hospital Universitari Vall d'Hebron
  • Dr. Vicente Andrés García
    Centro Nacional de Investigaciones Cardiovasculares Carlos III - Madrid
Fund: 299.999,75 €

New functions of the apoptotic genes in the development and stress of the myocardium

  • Dr. Daniel Sanchis Morales
    Institut Recerca Biomèdica de Lleida
Fund: 191.656,25 €

Pathophysiological and therapeutic evaluation of cardiomyocytes derived from induced pluripotent stem cells (iPS) from patients

  • Dra. Fabiana Silvia Scornik Gerzenstein
    Centre de Genètica Cardiovascular - IdIBGi Institut d'Investigació Biomèdica de Girona
Fund: 185.500,00 €

PREDICTAF: personalised early prediction of atrial fibrillation in at-risk subjects

  • Dra. Marta Sitges Carreño
    Institut d'Investigació Biomèdica August Pi i Sunyer
  • Dra. Gemma Piella Fenoy
    Universitat Pompeu Fabra
Fund: 297.401,25 €

Effects of CPAP treatment in de novo appearance of AF in patients with non-serious OSAS

  • Dr. Ermengol Vallès Gras
    Institut Hospital Mar d'Investigacions Mèdiques
Fund: 75.000,00 €

Diabetic cardiomyopathy: in search of a new therapeutic target

  • Dr. Manuel Vázquez Carrera
    Facultat de Farmàcia - Universitat de Barcelona
  • Dr. Juan Francisco Nistal Herrera
    Instituto de Investigación Marqués de Valdecilla - Universidad de Cantabria
Fund: 255.625,00 €

Intravenous administration of a modified HMG-CoA-reductase inhibitor: a promising heart-protection strategy in ischaemic heart disease. Deciphering benefits and mechanisms de action

  • Dra. Gemma Vilahur Garcia
    Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Fund: 192.687,50 €
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