Funded projects:
strokes and traumatic spinal cord and brain injury
In the 2016 Marató, which dealt with strokes and traumatic spinal cord and brain injury, 100 projects were presented and these were assessed by 47 scientists specialising in these diseases, according to their quality, methodology and relevance. This assessment was managed by the Agency for Health Quality and Assessment of Catalonia, of the Catalan Ministry of Health.
In accordance with the proposal of the scientific Advisory Committee of the Fundació La Marató de 3Cat, the Board agreed to distribute €9.686.188 to the following 37 research projects of excellence:
VALORA: assessment of motor function with proven free access tools
- Dr. Mariano Luis Alcañiz RayaInstitut d'Investigació i Innovació en Bioenginyeria - Universitat Politècnica de València
Fund: €199.750,00
Study of acute phase stroke mechanisms that favour the development of epilepsy
- Dr. José Álvarez SabínInstitut de Recerca Hospital Universitari Vall d'Hebron - VHIR
- Dra. Laia Grau LópezInstitut d'Investigació Hospital Universitari Germans Trias i Pujol - IIHGTP
Fund: €243.391,07
Damage to the blood-brain barrier in subarachnoid haemorrhage: clinical relevance, role of hyperglycaemia and effect of potentiation of endogenous antioxidant mechanisms. A translational study
- Dr. Sergio Amaro Delgado Institut d'Investigació Biomèdica August Pi i Sunyer, Hospital Clínic - IDIBAPS
- Dr. Carles Justicia MercaderInstitut d'Investigacions Biomèdiques de Barcelona - CSIC
- Dr. Pedro Ramos CabrerCentro de Investigación Cooperativa en Biociencias - CIC bioGune Bizkaia
Fund: €399.653,40
Multidisciplinary focus for modulation of neuroimmune crosstalk associated with pathological pain after chronic lesion of the spinal cord
- Dr. Pere Boadas VaelloFacultat de Medicina - Universitat de Girona
- Dr. Petr DubovýFaculty of Medicine - Masaryk University. Txèquia
Fund: €299.964,88
Lipoprotein biomarkers to determine inflammation of the carotid plaque in ischaemic stroke
- Dr. Pol Camps RenomInstitut d'Investigacions Biomèdiques Hospital de la Santa Creu i Sant Pau - IIBHSCSP
Fund: €197.575,00
Chemical optimisation of cerebral embolectomy: CHOICE study
- Dr. Ángel Chamorro SánchezInstitut d'Investigació Biomèdica August Pi i Sunyer, Hospital Clínic - IDIBAPS
- Dr. Sergio Martínez YelamosInstitut d'Investigació Biomèdica Hospital de Bellvitge - IDIBELL
- Dra. Elisa Cuadrado GodiaInstitut Hospital Mar d'Investigacions Mèdiques - IMIM
- Dra. María Ángeles Muchada LópezInstitut de Recerca Hospital Universitari Vall d'Hebron - VHIR
Fund: €394.373,75
New predictive biomarkers of optimal functional recovery and of good response to endovascular treatment of acute ischaemic stroke. PrOMISE study (somatosensory evoked POtentials MonItoring during acute ischaemic StrokE) Study
- Dr. Antoni Dávalos ErrandoInstitut d'Investigació Hospital Universitari Germans Trias i Pujol - IIHGTP
Fund: €154.287,50
Cerebrovascular accident, stroke unit, rehabilitation, optical, diffuse correlation spectroscopy, cerebral blood flow, cerebral self-regulation
- Dra. Raquel Delgado MederosInstitut d'Investigacions Biomèdiques Hospital de la Santa Creu i Sant Pau - IIBHSCSP
- Dr. Turgut DurduranInstitut de Ciències Fotòniques - ICFO
Fund: €298.000,00
Development new LRRC8/VRAC chloride channel inhibitors, a new key element in ischaemia
- Dr. Raúl Estévez PovedanoInstitut d'Investigació Biomèdica Hospital de Bellvitge - IDIBELL
- Dr. Rodolfo Lavilla GrifolsFacultat de Farmàcia i Ciències de l'Alimentació - Universitat de Barcelona
Fund: €299.936,53
EPIGENESIS Project. Epigenetic and genetic study combined with Integromica of data and functional analysis to find genes associated with neurological deterioration following ischaemic stroke
- Dr. Israel Fernández CadenasHospital Universitari Mútua de Terrassa
- Dr. Manel Esteller BadosaInstitut de Recerca Contra la Leucèmia Josep Carreras HUGTiP
- Dr. Cristòfol Vives BauzàHospital Universitari Son Espases - Palma
Fund: €396.250,00
Facing the challenges of acute care of people with stroke in the 21st century: achieving the highest rates of reperfusion treatments, eliminating inequalities in access and handling big data
- Dr. Miquel Gallofré LópezFundació Ictus
- Dr. Alfonso Valencia HerreraBarcelona Supercomputing Center
- Dr. Antonio Martínez YélamosInstitut d'Investigació Biomèdica Hospital de Bellvitge - IDIBELL
Fund: €348.501,14
Recovery of arm and hand movements in patients with cervical spinal cord injury using electrical spinal neuromodulation/stimulation assisted with an arm exoskeleton
- Dr. Guillermo García AlíasInstitut de Neurociències - Universitat Autònoma de Barcelona
- Dr. Jesús Benito PenalvaInstitut de Neurorehabilitació - Hospital Universitari Guttmann
- Dr. Juan C. Moreno SastoqueInstituto Cajal - CSIC
Fund: €399.945,00
Rare genetic variants associated with neonatal cerebral arterial infarction
- Dr. Alfredo García AlixHospital Sant Joan de Déu - Esplugues de Llobregat
Fund: €199.826,25
Motivational intervention for elderly people in geriatric post-stroke rehabilitation during admission and in transit to the home (IMAGINE)
- Dr. Marco InzitariParc Sanitari Pere Virgili
Fund: €172.760,00
Discovery and clinical usefulness of blood biomarkers in stroke-associated pneumonia
- Dra. Olga Maisterra SantosInstitut de Recerca Hospital Universitari Vall d'Hebron - VHIR
- Dr. Francisco Moniche ÁlvarezHospitales Universitarios Virgen del Rocío - Sevilla
Fund: €282.492,50
Effects of combined therapies of exercise, mindfulness and cognitive stimulation in cognition and neuroplasticity in patients with chronic ischaemic ictus
- Dra. Maria Mataró SerratInstitut de Neurociències - Universitat de Barcelona
- Dra. María José Durá MataInstitut d'Investigació Hospital Universitari Germans Trias i Pujol - IIHGTP
- Dr. Alberto García MolinaInstitut de Neurorehabilitació - Hospital Universitari Guttmann
Fund: €278.950,10
Faecal incontinence after ischaemic stroke (FINISH Study): understanding the physiopathological mechanisms and new frontiers in its treatment
- Dr. Mónica Millán TornéInstitut d'Investigació Hospital Universitari Germans Trias i Pujol - IIHGTP
Fund: €115.000,00
ITACAT: impact of thrombus analysis in stroke patients in Catalonia
- Dr. Carlos Molina CaterianoInstitut de Recerca Hospital Universitari Vall d'Hebron - VHIR
- Dra. Laura Dorado BouixInstitut d'Investigació Hospital Universitari Germans Trias i Pujol - IIHGTP
- Dra. Gisela Carolina de la TorreFundació Institut de Recerca Contra la Leucèmia Josep Carreras
Fund: €397.714,94
Help and care system for promoting physical activity in people with spinal cord injury
- Dra. Lluïsa Montesinos MagranerInstitut de Recerca Hospital Universitari Vall d'Hebron - VHIR
Fund: €199.934,75
Clinical grade combined cell, transplant therapy with small neuroprotective chemical products IPSC-derived en a rat model for central SCI regeneration of spinal cord pathways
- Dra. Victòria Moreno ManzanoCentro de Investigación Príncipe Felipe - València
Fund: €200.000,00
Combinatory treatment of neural precursor cells and a new nanoconjugate of fasudil for the clinical application in acute spinal cord injury
- Dr. Ferran Pellisé UrquizaInstitut de Recerca Hospital Universitari Vall d'Hebron - VHIR
- Dra. Maria Jesús Vicent DocónCentro de Investigación Príncipe Felipe - València
Fund: €300.000,00
Brain-intestine interaction in stroke: dysfunction of the intestinal barrier and immune responses as therapeutic targets
- Dra. Anna M. Planas ObradorsInstitut Investigacions Biomèdiques de Barcelona - IIBB CSIC
- Dr. Xabier Urra NuinInstitut d'Investigació Biomèdica August Pi i Sunyer, Hospital Clínic - IDIBAPS
- Dr. David Sancho MadridCentro Nacional de Investigaciones Cardiovasculares Carlos III - CNIC Madrid
Fund: €399.625,00
Anaemia or transfusion: a clinical dilemma in a patient with cranioencephalic trauma
- Dra. M. Antonia Poca PastorInstitut de Recerca Hospital Universitari Vall d'Hebron - VHIR
- Dr. Àngel Sandoval ÁlvarezInstitut de Ciències Fotòniques - ICFO
Fund: €299.461,25
Development of biomarkers of cerebral connectivity assessed by magnetic resonance during the recovery and rehabilitation of patients with cerebral infarction
- Dr. Josep Puig AlcántaraInstitut d'Investigació Biomèdica de Girona - IDIBGi
- Dra. Esther Duarte OllerInstitut Hospital Mar d'Investigacions Mèdiques - IMIM
- Dra. Cathy StinearCentre of Brain Research - University of Auckland. New Zealand
- Dr. Gustavo DecoCentre del Cervell i Cognició - Universitat Pompeu Fabra
- Dr. Gottfried Schlaug*Research and Academic Affairs - Harvard Medical School. United States
*The coordinating investigator and the research centre of this project proposed to the Board of the Fundació La Marató de 3Cat to waive the funding of two years of one of the co-ordinated subprojects and to adapt the work plan, without prejudice to the research. At the meeting of the Board held on 27 May 2021 it was agreed to amend the original sum of €398,113.75 awarded to the research project of La Marató 2016 led by the co-ordinating principal investigator Dr Josep Puig of the IDIBGI, allocating €53,352.50 corresponding to the part of the total amount of the project, which was not executed, to the purposes of the foundation. The total amount of the project remains at €344,761.25.
Fund: €398.113,75
GENIUS: genetic influences on the functional outcome of stroke
- Dra. Raquel Rabionet JanssenFundació per a la Recerca i la Docència Sant Joan de Déu
Fund: €200.000,00
Health, social and financial impact of providing access for acute stroke patients to integrated stroke care centres. Cost-utility study associated with the RACECAT trial
- Dra. Aida Ribera SoléInstitut de Recerca Hospital Universitari Vall d'Hebron - VHIR
Fund: €169.250,00
Smartphone application to encourage healthy modification of lifestyle and monitoring of therapeutic compliance in the secondary prevention of strokes in multiple centres in Catalonia
- Dr. Marc Ribó JacobiInstitut de Recerca Hospital Universitari Vall d'Hebron - VHIR
Fund: €149.990,00
Musical learning and singing in cerebral recovery: efficacy of music-based interventions improved taking into account sociomotivational factors in stroke rehabilitation
- Dr. Antoni Rodríguez FornellsInstitut d'Investigació Biomèdica Hospital de Bellvitge - IDIBELL
- Dr. Josep Lluís Arcos RosellInstitut Investigació Intel·ligència Artificial - IIIA CSIC
- Dr. Teppo SärkämöCognitive Brain Research Unit - University of Helsinki. Finland
Fund: €399.619,54
Influence of time to control of arterial pressure on growth of the haematoma in patients with acute intracerebral haemorrhage
- Dr. David Rodríguez LunaInstitut de Recerca Hospital Universitari Vall d'Hebron - VHIR
- Dra. Laura Llull EstranyInstitut d'Investigació Biomèdica August Pi i Sunyer, Hospital Clínic - IDIBAPS
Fund: €274.915,39
Influence of diesel motor particles as atmospheric pollutants in brain lesions and repair after experimental stroke
- Dra. Anna Rosell NovelInstitut de Recerca Hospital Universitari Vall d'Hebron - VHIR
Fund: €200.000,00
Computerised tomography of perfusion characterised by lack of clinical improvement after rechannelling in patients with acute ischaemic stroke (CTP_AFT_REC)
- Dra. Marta Aurora Rubiera del FueyoInstitut de Recerca Hospital Universitari Vall d'Hebron - VHIR
Fund: €199.955,00
Blood markers of the quality of fat in the diet and incidence of ischaemic stroke in a Mediterranean population
- Dr. Aleix Sala VilaBarcelona Beta Brain Research Center
Fund: €160.750,00
Effects of age in cranioencephalic trauma; mechanical properties
- Dr. David Sánchez MolinaEscola Tècnica Superior d'Enginyeria Industrial - Universitat Politècnica de Catalunya
- Dr. Mehdi Shafieian*Amir Kabir University of Technology - Teheran
*In the signing of the agreement, due to the legal impossibility of transferring the first year's funds assigned to the institution managing the subproject, University of Iran, because of the legal restrictions that the European Union (EU) has imposed on the country in which the institution is located, it is not possible to make the corresponding payment to this centre. The coordinating investigator and his research centre proposed to the Board of the Fundació La Marató de 3Cat to achieve from a single research line the part of the objectives proposed for this subproject, which would become a single-centre project. At the meeting held on 23 January 2020 the Board approved the proposal and will fund the single-centre project with a budget of €197,875.00. Since the project coordinated from Teheran, with a budget of €101,413.75 can hardly be carried out; it was agreed that, if this finally is the case, this sum of €101,413.75 will be allocated to the Foundation's purposes of research and awareness-raising.
Fund: €299.288,75
Prospective study of the prediction of growth of the cerebral haemorrhage using CT perfusion
- Dra. Yolanda Silva BlasInstitut d'Investigació Biomèdica de Girona Hospital Dr. Josep Trueta - IDIBGI
Fund: €62.500,00
Random controlled trial on the potentiating effect transcranial random noise stimulation (TRNS) in the cognitive rehabilitation of patients with traumatic brain damage
- Dr. Josep M. Tormos MuñozInstitut de Neurorehabilitació - Hospital Universitari Guttmann
Fund: €195.000,00
Modulation of the perineural networks using physical exercise after spinal cord injury in animal models: plasticity versus stability of the neural circuits
- Dra. Esther Udina BonetFacultat de Medicina - Universitat Autònoma de Barcelona
- Dr. Joost VerhaagenNetherlands Institute for Neuroscience - Royal Netherlands Academy of Sciences. Amsterdam
Fund: €300.000,00
Efficacy of a programme of stability exercises of core in dynamic balance when seated, control of trunk and functional rehabilitation in patients with subacute stroke : randomised clinical trial
- Dr. Gerard Urrutia CuchíInstitut d'Investigacions Biomèdiques Hospital de la Santa Creu i Sant Pau - IIBHSCSP
Fund: €199.412,51